Some vaginal moisturizers like gels or suppositories are made of hyaluronic acid (HA), a super large molecule that is naturally produced throughout the body.
Cells can be bound together by attachment to one another or via a glue-like matrix. The glue-like matrix is a meshwork of fibrous proteins embedded in a watery, gel-like substance (see figure below). Interwoven within the matrix are three groups of large molecules: (1) collagen and elastin; (2) adhesive glycoproteins; and (3) proteoglycans and hyaluronic acid.
Hyaluronic acid is a big molecule. How big is it? A water molecule is 18 Dalton. A glucose is 180 Dalton, 10 times bigger than water. But a hyaluronic acid molecule is about 7 million Dalton. It is about 30-40 thousand times bigger than a glucose molecule.
Due to its jumbo size, the vaginal skin cannot absorb hyaluronic acid because the skin barrier naturally blocks large molecules from entering the skin. As a result, hyaluronic acid delivered to the vagina cannot enter the vaginal lining skin tissue to nourish it.
Then why you feel better after you use a hyaluronic acid gel or suppository?
This is because hyaluronic acid traps water and can release it slowly as a great moisturizer. It delivers water to the dried tissue surface to quench thirst. When dryness is relieved, you feel better. But it does not quench hunger of the atrophied tissue. As a result, the atrophy continues because the tissue only "drinks" water but not "ingests" any nutrients.
Being a water trapper but not a usable nutrient, hyaluronic acid does not reverse vaginal atrophy.
Therefore, hyaluronic acid based gels or suppositories only provide a short-term relief. When vaginal atrophy becomes more severe, painful sex cannot be relieved by just moisturizing. Users of hyaluronic acid start to search for a more effective product. This is the time when they find NeuEve.
NeuEve is more effective than hyaluronic acid because it not only moisturizes but also nourishes the dried and atrophied tissue. It reverses vaginal atrophy by nutritional supplement like calcium for osteoporotic bones.
Additionally, NeuEve promotes vaginal health by supporting a Lactobacillus-dominant microbiome, which helps protect against common infections like BV and yeast. With regular use, NeuEve can enhance vaginal resilience. In contrast, hyaluronic acid-based products, while providing moisture, do not improve vaginal resistance to infection. By moisturizing without bolstering natural defenses, these products may actually increase susceptibility to yeast infections, as some of our customers have reported after using them.
Many hyaluronic acid based products cost more than NeuEve, but are much less effective. For best feminine health maintenance, it is better to start with NeuEve or convert to NeuEve if you are currently on hyaluronic acid based products.
To date, over 100,000 women with vaginal atrophy have used NeuEve and found relief. Among them, many are previous users of hyaluronic acid.
https://www.neueve.com/blog/neueve-the-best-product-for-painful-sex-relief/
Disclaimer: This article is for information purposes only. It is about natural products, nutrients, and/or methods for managing discomforts associated with vaginal dysbiosis (not a true infection or disease). It is not medical advice for the treatment of any disease.
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Customer feedback
Coming Back
I used NeuEve Silk for a few months and noticed a distinct difference in how moist I was, but decided to try a competitor that uses hyaluronic acid as a test. It did not perform as well (in fact I regressed to pre-Silk stage) so I am returning to Silk.